These factors are included in a "Manual J" calculation. Contractors who make these calculations before recommending a size can take a couple of hours collecting the information and making the calculation. If your contractor doesn't do it, there are services that will do it for around $99. If you're feeling particularly on the ball, there are also free online calculators.
Lennox, on the other hand, is probably the most expensive unit out there and I can’t stand them.  In our (humble?) experience, they have a horrible logistics chain, making repair parts difficult to come by (sometimes taking weeks), poor customer service, and the parts cost three times as much. That’s not what this article is about, so read more in: Carrier vs. Lennox Furnace Review.
As a person with severe mold allergies, I live in a the South where the climate naturally breeds molds.We noticed a difference when we had our ducts cleaned.The company used a vacumn type system and covered all of our vents with plastic that was held up by the suction. We had no damage, no leaking dust/dirt back into the house and it took several hours. I think if you use a reputable company it makes the world of difference. Now we use better air filters and also have a UV light to prevent mold growth on ours system.We 'd do it again when the time comes. From your car's air filter to your dryer...anything works more efficiently when it is not filthy dirty.That's just common sense.
Most organizations concerned with duct cleaning, including EPA, NADCA, NAIMA and the Sheet Metal and Air Conditioning Contractors' National Association (SMACNA) do not currently recommend the routine use of sealants to encapsulate contaminants in any type of duct. Instances when the use of sealants to encapsulate the duct surfaces may be appropriate include the repair of damaged fiber glass insulation or when combating fire damage within ducts. Sealants should never be used on wet duct liner, to cover actively growing mold, or to cover debris in the ducts, and should only be applied after cleaning according to NADCA or other appropriate guidelines or standards.

Whether you’re looking for air conditioning maintenance, air conditioner repair, or a new air conditioning system, Sears Home Services can help. We’re your best, most-trusted option for fast, quick, and easy local service, repair, and maintenance of your home air conditioning system. If your air conditioner isn’t cooling or your central air conditioner is leaking water, we’ll connect you to the best local AC repair service technicians in the business.We have local technicians in your neighborhood that are highly trained, licensed, vetted, and guaranteed to help fix all of your air conditioning needs.
Humidifiers/Dehumidifiers: Humidifiers add needed moisture to the air in winter and very dry climates. Dehumidifiers remove dampness any time of the year. Central air conditioners dehumidify too, but in very humid climates, you might want to remove humidity without also cooling the air. You have a good range of options for both of these HVAC accessories. Whole-house humidifiers cost $350 to $800 installed, while dehumidifiers are $1,250 to $2,000 or slightly more.
Central home air conditioner service systems consist of two major components: a condensing unit that sits outside your house, and the evaporator coil (often referred to as an A-coil) that sits in the plenum of your furnace or air handler. The refrigerant in the A-coil picks up the heat from your home and moves it to the outdoor condensing unit. The condensing unit fan blows outside air through the condensing coil to remove the heat. The condensing unit houses the three parts replaceable by a DIYer: the AC contactor, the start/run capacitor(s) and the condenser fan motor. The condensing unit also houses the compressor, but only a pro can replace that. The A-coil has no parts that can be serviced by a DIYer.
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