They are also often harder to install. A proper location on the roof must be selected that can support the weight of the unit. Then a platform must be built and a drain pipe for the unit must be run along the roof to avoid problems with mold and corrosion. A crane must be used to lift the unit onto the roof while a team guides it into place and hooks it up.
In addition, the service provider may propose applying chemical biocides, designed to kill microbiological contaminants, to the inside of the duct work and to other system components. Some service providers may also suggest applying chemical treatments (sealants or other encapsulants) to encapsulate or cover the inside surfaces of the air ducts and equipment housings because they believe it will control mold growth or prevent the release of dirt particles or fibers from ducts. These practices have yet to be fully researched and you should be fully informed before deciding to permit the use of biocides or chemical treatments in your air ducts. They should only be applied, if at all, after the system has been properly cleaned of all visible dust or debris.
The cooling coils the air comes into contact with appear to need UV-C lights on them in humid climates. That's the biggest thing. If the ducts have never been cleaned, then getting that done goes without saying. But those coils need to be cleaned, disinfected, and then UV-C light(s) installed to prevent mold & bacteria build-up in the future on them. That appears to be chiefly responsible for the dirty laundry and/or sour milk smell coming from forced-air AC systems in humid regions.
I read your article with interest and think it is a good start. One service that is always talked about is fogging ductwork for sanitizing. Many companies offer this service for disinfecting or adding a clean smell to the ductwork. Before any chemical or disinfectant is used, please read the MSDS (Material Safety Data Sheet). You might be surprise on what you are putting into the air stream. This is a high profit service and should be explored thoroughly before purchasing,
A year and a half ago (fall of 2015) we replaced the furnace and air conditioner. From what we could determine this was the third forced air furnace and second air conditioner unit for the house. As part of the installation, we changed out the two 6″ ducts feeding the second floor with 8″ ducts. The idea was to get more cold air to the second floor in the summer. It worked and for the first time the second floor and first floor temperatures were the same when the air conditioner was running. Of course, to make the system work I close down upstairs duct damper doors in the winter and open them up in the summer.

I live in a 1950's ranch house in the South. The prior owners were smokers. Based on recommendations from one of the local conservation organizations, I decided to have a home energy audit done. As part of their findings, they recommended additional insulation in the attic and duct cleaning and sealing. This turned out to be a very problematic process. In terms of the ducts, it was necessary to remove the metal grates. However, these grates had been painted over many times and shoe molding covered the bottom of the grates. The vendor was not able to remove the grates without damaging them in the process. Because these grates dated back to the 1950's, it was difficult to find appropriate replacements. The ones I finally discovered were correct except they were 1/4" wider. This meant that the shoe molding had to be carved out. The duct cleaner could not provide any assistance with this problem. It took me a month of long evenings replacing the vent covers myself, carefully chiseling out the shoe molding and repainting. In terms of the extra installation in the attic, the same vendor used blow in insulation. Unfortunately, they did not recognize that the 13 floodlights whose mounting extended into the attic were not designed to be buried under insulation. The problem manifested itself in terms of expensive flood light bulbs failing continually. So, I had to have all of the light housings replaced. Yet another unexpected expense. Despite the expense, pain and suffering, I cannot report any improvement in my heating costs or the "quality" of the air. To be fair, I do not have any allergies and did not undertake this for air quality improvements but rather heating efficiency improvements.
PickHVAC Tips: Oil burns dirty, so it is important to have your plenum and ducts checked to see if they should be cleaned when replacing an oil furnace. If you don’t clean the plenum and ducts when replacing the furnace, the new furnace might not run as efficiently and comfortably as possible due to restricted airflow. This can also reduce the oily smell sometimes associated with oil furnaces.
I had my ducts somewhat cleaned December 22, 2014. The hose of the machine the technitian used did not fit in some of my vents, therefore, he did not clean them. But I still paid $428.00 for the service. I will be calling the company on Monday, and kindly ask them to come back and clean the ducts they did not as they did not fullfill their part of the service.
The heat pump gained popularity in the 1950s in Japan and the United States.[13] Heat pumps can extract heat from various sources, such as environmental air, exhaust air from a building, or from the ground. Heat pumps transfer heat from outside the structure into the air inside. Initially, heat pump HVAC systems were only used in moderate climates, but with improvements in low temperature operation and reduced loads due to more efficient homes, they are increasing in popularity in cooler climates.

"Customer service was great, and the price was in-line with other places, and fast service. We had a whole replacement of the outside and inside. I would have liked to see a better install for the furnace and new thermostat - the new thermostat should have gone where the old one was, and even tho the new furnace was a tight fit, they didn't offer to come back and repair the case molding, or give me a discount on the damage done, and I believe they should have put a disconnect box on the outside of the home, to make it easier for any future repairs needed. Other than that, am very happy with the cooling and heating!"