How exactly do you expect to kill or remove mold without it ? You can’t even clean your hvac systems coils without moisture of some type ,if you use a steam cleaner you can literally clean the whole system minus the electronics . You should do more research and possibly talk to people who do the work before posting , but don’t listen to me i only have a class A contractor license ,epa license , install /repair hvacs , rent and flip houses for a living .
As a person with severe mold allergies, I live in a the South where the climate naturally breeds molds.We noticed a difference when we had our ducts cleaned.The company used a vacumn type system and covered all of our vents with plastic that was held up by the suction. We had no damage, no leaking dust/dirt back into the house and it took several hours. I think if you use a reputable company it makes the world of difference. Now we use better air filters and also have a UV light to prevent mold growth on ours system.We 'd do it again when the time comes. From your car's air filter to your dryer...anything works more efficiently when it is not filthy dirty.That's just common sense.

Duct cleaning is a complete scam, I was a “duct cleaning technician” for a whole week before I was fired for not upselling elderly widowed women $2000 extra for “toxic mold remediation” when their ducts were spotless to begin with. The last two days I was employed there I worked as a “helper” alongside a technician thats been with the company 7 years. He scammed every customer on mold and would at times get as much as $2500 extra for treating “toxic mold” in a typical 3 bedroom house in the suburbs. Wait…it gets even better, the “Biocide” the company used was simply a cheap $4.99 per gallon bought at Home Depot air freshener with no anti-microbial properties that was fogged into the HVAC system for 5 minutes, maybe using 1/2 cup of the stuff. In order to provide the customer with evidence of “mold infestation” the technician would be given bogus mold tests that always resulted in “toxic spores present” regardless if you swabbed the actual duct or nothing at all. Not to mention the actual duct cleaning job (typically $400) did basically nothing and the homeowner could’ve done a better job with a shopvac
Central, "all-air" air-conditioning systems (or package systems) with a combined outdoor condenser/evaporator unit are often installed in North American residences, offices, and public buildings, but are difficult to retrofit (install in a building that was not designed to receive it) because of the bulky air ducts required. (Minisplit ductless systems are used in these situations.) Outside of North America, packaged systems are only used in limited applications involving large indoor space such as stadiums, theatres or exhibition halls.
Your HVAC unit and air ducts deliver heated or cooled air throughout your home year-in and year-out. The air your HVAC unit produces travels through your ductwork and heats or cools your home via the air vents in each room. The dust and other particles in your home’s air are known as particulate matter, which the EPA defines as "a complex mixture of extremely small particles and liquid droplets." The EPA also notes that "particle pollution is made up of a number of components, including acids (such as nitrates and sulfates), organic chemicals, metals, and soil or dust particles." Having clean air ducts means fewer of these particles moving through your home. If you remove your furnace filter and hold it up to the light, you can probably see several hundred of these minuscule particles floating in the air. 
Some systems include an "economizer mode", which is sometimes called a "free-cooling mode". When economizing, the control system will open (fully or partially) the outside air damper and close (fully or partially) the return air damper. This will cause fresh, outside air to be supplied to the system. When the outside air is cooler than the demanded cool air, this will allow the demand to be met without using the mechanical supply of cooling (typically chilled water or a direct expansion "DX" unit), thus saving energy. The control system can compare the temperature of the outside air vs. return air, or it can compare the enthalpy of the air, as is frequently done in climates where humidity is more of an issue. In both cases, the outside air must be less energetic than the return air for the system to enter the economizer mode.
"OTHER THAN A SMALL SCHEDULING HICK-UP THEIR SERVICE WAS EXCELLENT. JOSH THE TECHNICIAN THAT PREFORMED THE DIAGNOSTICS AND REPAIR WAS EXTREMLEY PROFESIONAL AND FRIENDLY â ¦ HE WAS ABLE TO FIND THE PROBLEM WHICH WAS VERY DIFFICULT TO FIND AND FIX THE PROBLEM. I WISH THAT ALL HOME SERVICE PEOPLE WERE AS GOOD AS HE WAS. I WOULD HIRE AGAIN...JOB WELL DONE !!!"
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