The performance of vapor compression refrigeration cycles[26] is limited by thermodynamics. These air conditioning and heat pump devices move heat rather than convert it from one form to another, so thermal efficiencies do not appropriately describe the performance of these devices. The Coefficient-of-Performance (COP) measures performance, but this dimensionless measure has not been adopted. Instead, the Energy Efficiency Ratio (EER) has traditionally been used to characterize the performance of many HVAC systems. EER is the Energy Efficiency Ratio based on a 35 °C (95 °F) outdoor temperature. To more accurately describe the performance of air conditioning equipment over a typical cooling season a modified version of the EER, the Seasonal Energy Efficiency Ratio (SEER), or in Europe the ESEER, is used. SEER ratings are based on seasonal temperature averages instead of a constant 35 °C (95 °F) outdoor temperature. The current industry minimum SEER rating is 14 SEER.[27][dead link]
I am NADCA Certified Air Systems Cleaning Specialist. Over the year I have learned on simple answer to this questions: there air duct cleaners and there are pretenders. There will be no benefit at all if you use on the very cheap pretender because they will not really clean anything. On the other hand if you call a qualified air duct cleaner with a NADCA Certification you will, like 99% of my customers, report improvement with your respiratory problems, you will see less dust and the job will pay for itself with energy savings and repair prevention.
You might also want to check your home for thermal insulation if you live in extreme heat or freezing temperatures. Insulation keeps the heat and cool air in your home, which can lead to a lower electric bill. If the heated or cool air leaks out, your system turns on more often. There are various types of insulation that you can install in your home and a home energy auditor can point out the best places for it in your house.
Do you live in a historic home and want to tie your new system in to work with existing features? The price will go up to do the job right. All of these things add up to slow down the HVAC company, which takes more time, which costs more money for labor and parts. This is especially true if they are a legitimate company which is licensed, bonded and insured. Simply put, this is the “X-Factor” in your HVAC installation cost. Again, you could get people to do it for cheaper…but you won’t be happy with the results, I promise.
Central home air conditioner service systems consist of two major components: a condensing unit that sits outside your house, and the evaporator coil (often referred to as an A-coil) that sits in the plenum of your furnace or air handler. The refrigerant in the A-coil picks up the heat from your home and moves it to the outdoor condensing unit. The condensing unit fan blows outside air through the condensing coil to remove the heat. The condensing unit houses the three parts replaceable by a DIYer: the AC contactor, the start/run capacitor(s) and the condenser fan motor. The condensing unit also houses the compressor, but only a pro can replace that. The A-coil has no parts that can be serviced by a DIYer.
#3 The ONLY time Duct cleaning is needed is when the home had a fire, Bad roof leak on to FIBERGLASS ductwork or house sat vacant for many years with out the air running. And its better to replace than to do “abrasive” duct cleaning. If the duct cleaning has a rotating brush it will remove part of the glue that is holding the Fiberglass in the ducts together, PERIOD no matter how much the say it don’t because the brush is soft.

Despite such anecdotal experiences, there's no scientific evidence that regular residential air duct cleaning improves air quality, according to a 1997 brochure published by the Environmental Protection Agency. Laureen Burton, senior scientist in the EPA Indoor Environments Division, says that while the document is nearly two decades old, the science hasn't changed and the agency stands by its recommendations.

A small number of products are currently registered by EPA specifically for use on the inside of bare sheet metal air ducts. A number of products are also registered for use as sanitizers on hard surfaces, which could include the interior of bare sheet metal ducts. While many such products may be used legally inside of unlined ducts if all label directions are followed, some of the directions on the label may be inappropriate for use in ducts. For example, if the directions indicate "rinse with water", the added moisture could stimulate mold growth.
If you believe that the AC's not working or you're getting little or no cold air, check these three things first. Make sure all the registers in the house are wide open. Then be sure the furnace filter is clean. Then go outside and clean off the condenser coils (Photo 2). If several registers were closed or the filter was clogged, the reduced airflow could have caused the evaporator coil to ice up and stop cooling your home. If you've changed the filter and opened all the registers and you're still not getting airflow at the registers, deice the A-coil. Move the thermostat mode switch from “Cooling” to “Off” and move the fan switch from “Auto” to “On.” Let the blower run for at least 30 minutes or until there's good airflow at the registers. Then turn the AC back on to test it. If it works for the next 12 hours, you've solved the problem.